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主营:抗体,重组蛋白,细胞培养基和分子生物学试剂盒
℡ 4000-520-616
℡ 4000-520-616
Usbio/029610-ML750 Rabbit Anti-SIRT5 (NAD-dependent Deacetylase Sirtuin 5, SIR2-like Protein 5, SIR2L5) (MaxLight 750)/029610-ML750/100ul
产品编号:029610-ML750
市  场 价:¥16420.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$821.00
品      牌: Usbio
公      司:United States Biological
公司分类:
Usbio/029610-ML750 Rabbit Anti-SIRT5 (NAD-dependent Deacetylase Sirtuin 5, SIR2-like Protein 5, SIR2L5) (MaxLight 750)/029610-ML750/100ul
商品介绍

MaxLight™750 is a new Near IR stable dye conjugate comparable to DyLight™750, Alexa Fluor™700 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (759nm); Emission (780nm); Extinction Coefficient 240,000.

Sirtuin (SIRT5) is known as a nicotinamide adenine dinucleotide- dependent deacetylase that is a member of the silent information regulator 2 (Sir2) family of proteins that is important in aging, metabolism and disease. SIRT5 is expressed in a variety of tissues. Two different isoform have been described. Isoform 1 is reported to be express in the mitochondria and cytoplasm while isoform 2 appears to be localized to the mitochondria only. SIRT5 has also been linked to many primate-specific functions. SIRT5 has recently been implicated as having a role in adaptation to fasting, caloric restriction and high protein diets.
Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 0.5ug/mlImmunohistochemistry: 1:500Optimal dilutions to be determined by the researcher.
Positive Control
HeLa cell lysate
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Synthetic linear peptide corresponding to human SIRT5 (KLH). Species sequence homology: chimpanzee and rhesus macaque (100%).
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™750.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SIRT5. Species Crossreactivity: rat.
References
1. Matsushita, N., et al. (2011). Genes Cells. 16(2):190-202. 2. Nakagawa, T. and Guarente, L. (2009). Aging (Albany NY). 1(6):578-581. 3. Mahlknecht, U., et al. (2006). Cytogenet Genome Res. 112(3-4):208-212.
品牌介绍
USbio全称United States Biological,位于麻省斯万普斯科特(Swampscott, MA)。全美**的抗原抗体和生化试剂供应商,目前向全球六十余个国家的科研工作者提供约50,000种抗体、抗原和生化试剂,以质量**闻名。主要产品种类包括:抗体、生化试剂、基因克隆相关产品、培养基、生长因子等细胞因子、分子生物学试剂。美国US Biological公司是生物化学和生物学试剂的专业生产商,产品服务于免疫学,分子生物学,分子遗传学,体外诊断,组织培养等科研领域。产品精确度高,质量稳定,产品数量巨大,提供70,000多种抗体、抗原和生化试剂等。
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