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当前位置: 首页 > 产品中心 > Kits and Assays > Usbio/A2298-88A3 Anti-APOBEC1, Human, Control Peptide (Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 1)/100ug/A2298-88A3

Usbio/A2298-88A3 Anti-APOBEC1, Human, Control Peptide (Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 1)/100ug/A2298-88A3

  • 产品编号: A2298-88A3
  • 美  元  价: $347.00
  • 市  场  价: ¥6940.00
  • 品       牌:
  • 产       地: 美国(厂家直采)
  • 公       司: United States Biological
  • 产品分类:
  • 公司分类: Kits and Assays
Usbio/A2298-88A3  Anti-APOBEC1, Human, Control Peptide (Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 1)/100ug/A2298-88A3
  • Usbio/A2298-88A3  Anti-APOBEC1, Human, Control Peptide (Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 1)/100ug/A2298-88A3
商品介绍
RNA editing is an important mechanism for regulating genetic plasticity through the generation of alternative protein productsfrom a single structural gene. Substitutional RNA editing employsa variety of genetic mechanisms, the biochemical basis of whichhas been elucidated following the development of in vitro assaysthat recapitulate important elements of this process. There are two typesof substitutional RNA exist in mammals, namely A-to-I and C-to-URNA editing. The best-characterized example of C-to-U RNA editing involves the nuclear transcript encoding intestinal apolipoprotein B(apo B)). Apo B RNA editing changes a CAA to a UAA stop codon,generating a truncated protein, apoB48. The functional complex includes a minimal corecomposed of apobec-1 and ACF, that functionas an adaptor protein by binding both the deaminase and the RNA substrate. The RNA binding proteins also include CUGBP2 which along with Apobec-1 binds to the consensus binding sequence UUUN (A/U) U, present in c-myc, VEGF and Cyclooxygenase-2 (COX2).||Apobec-1, a 236aa protein in human (chr 12p13.1) an RNA specific cytidine deaminase, is essential but not efficient for apo B editing activity, there being a requirement for other protein factor. Apobec-1 is a dimer with the composite active site assembled through interaction of each monomer; In addition it is an RNA-binding protein that binds to the consensus sequence UUUN (A/U) U located within the terminal loop of apo B RNA. But finally it forms the minimal component of the core-editing enzyme along with ACF.||Source:|16-aa peptide from human Apobec-1||Location:|~C-terminus||Applications:|ELISA: Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies.||Storage and Stability:|Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
品牌介绍

USBio全称United States Biological,位于麻省斯万普斯科特(Swampscott, MA)。全美著名的抗原抗体和生化试剂供应商,目前向全球六十余个国家的科研工作者提供约50,000种抗体、抗原和生化试剂,以质量**闻名。主要产品种类包括:抗体、生化试剂、基因克隆相关产品、培养基、生长因子等细胞因子、分子生物学试剂。美国US Biological公司是生物化学和生物学试剂的专业生产商,产品服务于免疫学,分子生物学,分子遗传学,体外诊断,组织培养等科研领域。产品精确度高,质量稳定,产品数量巨大,提供70,000多种抗体、抗原和生化试剂等。

We are committed to reducing the cost of research with value, integrity and a truly personal buying experience. We believe in answering all inquiries within a few hours of receipt. You always get to speak with humans (our rabbits are shy). Our technical support department is comprised of scientists with decades of experience. We will promptly and thoroughly answer your inquiries and enjoy helping guide you through protocols whether it be for our products or your personal research.

United States Biological's biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications and settings, including genomic research, biotechnology, pharmaceutical development and the diagnosis of disease. Products are available from affordable research quantities to larger bulk amounts for process development and production. Our customers include most of the leading pharmaceutical and biotechnology companies located in the US and abroad.

International Customer service and technical support is available in all countries; hundreds of employees and distributors provide excellent service worldwide.


部分产品展示:

NGAL(Lipocalin2)Antibodies   

Cat#ProductNameHostSourceClone# 

167733NGALMousePorcine28 

L2499-14ANGALMouseHuman13A128 

L2499-14CNGALMouseHuman13A129 

L2499-14DNGALMouseHuman13A130 

L2499-14ENGALRatMouse13A131 

L2499-14FNGALRatMouse13A132 

L2499-14GNGALMouseCanine13A133 

L2499-14HNGALMouseCanine13A134 

L2499-14MNGAL(Biotin)RatMouse13A135 

L2499-14NNGAL(Biotin)MouseCanine13A136 

L2499-15NGALMouseHuman6F154 

L2499-15CNGAL(Biotin)MouseHuman6F154 

L2499-16NGALMouseHuman6F155 

L2499-17BNGALMouseRat7F2 

L2499-17CNGALMouseRat7F3 

L2499-17DNGAL(Biotin)MouseRat7F1 

L2499-17ENGALMouseHuman8D2 

L2499-17GNGALMousePorcine048-17 

RecombinantNGALAntigens   

Cat#ProductNameSourceAntigen  

168622Lipocalin2,RecombinantRecombinantHumanfromE.coli 

168623Lipocalin2,RecombinantRecombinantMousefromE.coli 

168624Lipocalin2,RecombinantRecombinantRatfromE.coli  

168625Lipocalin2,RecombinantRecombinantCaninefromE.coli 

168626Lipocalin2,RecombinantRecombinantPorcinefromE.coli 

168627Lipocalin2,RecombinantRecombinantMonkeyfromE.coli 

NGALELISAKits(96Tests)   

Cat#ProductNameDetectionRangeSensitivity  

27143NeutrophilGelatinaseAssociatedLipocalin(NGAL)

 BioAssay™ELISAKit(Human)31.2-2000pg/ml13.5pg/ml  

27144NeutrophilGelatinaseAssociatedLipocalin(NGAL)

 BioAssay™ELISAKit(Rat)6.25-400pg/ml2.84pg/ml  

27145NeutrophilGelatinaseAssociatedLipocalin(NGAL) 

BioAssay™ELISAKit(Mouse)0.156-10ng/ml0.066ng/ml 

27146NeutrophilGelatinaseAssociatedLipocalin(NGAL) 

BioAssay™ELISAKit(Porcine)1.56-100ng/ml0.57ng/ml  

Nourseothricin   

Gram-negativebacteria   

 MIC*(ug/ml)Selectionconc.(ug/ml)  

Escherichiacoli4168250  

Francisellatularensis-5  

Pseudomonasaeruginosa50100  

Gram-positiveBacteria   

 MIC*(ug/ml)Selectionconc.(ug/ml)  

Bacillussubtilis510  

Enterococcusfaecium8-256500  

Staphylococcusaureus-1250  

Streptomycetes  

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